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Chromatin Stability at Low Concentration Depends on Histone Octamer Saturation Levels

Studies on the stability of nucleosome core particles as a function of concentration have indicated a lower limit of ∼5 ng/μL, below which the complexes start to spontaneously destabilize. Until recently little information was available on the effect of low concentration on chromatin. Using the well...

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Bibliografiske detaljer
Main Authors: Hagerman, Thomas A., Fu, Qiang, Molinié, Benoit, Denvir, James, Lindsay, Stuart, Georgel, Philippe T.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717262/
https://ncbi.nlm.nih.gov/pubmed/19254554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.070
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