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Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins
Two cellular proteins, stromal interaction molecule 1 (STIM1) and Orai1, are recently discovered essential components of the Ca(2+) release activated Ca(2+) (CRAC) channel. Orai1 polypeptides form the pore of the CRAC channel, while STIM1 plays the role of the endoplasmic reticulum Ca(2+) sensor req...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718249/ https://ncbi.nlm.nih.gov/pubmed/19403622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.170662 |
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