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Molecular and Mesoscale Mechanisms of Osteogenesis Imperfecta Disease in Collagen Fibrils

Osteogenesis imperfecta (OI) is a genetic disorder in collagen characterized by mechanically weakened tendon, fragile bones, skeletal deformities, and in severe cases, prenatal death. Although many studies have attempted to associate specific mutation types with phenotypic severity, the molecular an...

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Detalhes bibliográficos
Main Authors: Gautieri, Alfonso, Uzel, Sebastien, Vesentini, Simone, Redaelli, Alberto, Buehler, Markus J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718154/
https://ncbi.nlm.nih.gov/pubmed/19651044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.04.059
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