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Enzymatic Activity versus Structural Dynamics: The Case of Acetylcholinesterase Tetramer

The function of many proteins, such as enzymes, is modulated by structural fluctuations. This is especially the case in gated diffusion-controlled reactions (where the rates of the initial diffusional encounter and of structural fluctuations determine the overall rate of the reaction) and in oligome...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gorfe, Alemayehu A., Lu, Benzhuo, Yu, Zeyun, McCammon, J. Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718147/
https://ncbi.nlm.nih.gov/pubmed/19651048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.033
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