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Prolactin confers resistance against cisplatin in breast cancer cells by activating glutathione-S-transferase
Resistance to chemotherapy is a major obstacle for successful treatment of breast cancer patients. Given that prolactin (PRL) acts as an anti-apoptotic/survival factor in the breast, we postulated that it antagonizes cytotoxicity by chemotherapeutic drugs. Treatment of breast cancer cells with PRL c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718070/ https://ncbi.nlm.nih.gov/pubmed/19443905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp120 |
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