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Estrogen Receptor-α Mediates the Epidermal Growth Factor-Stimulated Prolactin Expression and Release in Lactotrophs

Epidermal growth factor (EGF) is a potent regulator of cell function in many cell types. EGF-receptor (EGFR/ErbB1)-activated Erk1/2 has been reported to activate estrogen receptor (ER) in an estrogen (E2)-independent manner. In the pituitary lactotrophs, both EGF and E2 stimulate prolactin (PRL) rel...

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Detalhes bibliográficos
Main Authors: Ben-Jonathan, Nira, Chen, Shenglin, Dunckley, Joseph A., LaPensee, Christopher, Kansra, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646526/
https://ncbi.nlm.nih.gov/pubmed/18832099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0756
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