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Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans

BACKGROUND: There is evidence from animal studies that serotonin (5-HT) can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on individual variability in response to opioid treatment of...

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Main Authors: Kosek, Eva, Jensen, Karin B, Lonsdorf, Tina B, Schalling, Martin, Ingvar, Martin
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717925/
https://ncbi.nlm.nih.gov/pubmed/19570226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-37
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