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Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val(158)met Polymorphism
Increased pain sensitivity after opioid administration (opioid-induced hyperalgesia) and/or repeated painful stimuli is an individually varying and clinically important phenomenon. The functional polymorphism (val(158)met) of the Catechol-O-methyltransferase (COMT) gene regulates the metabolism of d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695541/ https://ncbi.nlm.nih.gov/pubmed/19547755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006016 |
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