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MIF-deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance and associated atherosclerotic disease
Chronic inflammation in white adipose tissue (WAT) is positively associated with obesity, insulin resistance (IR) and the development of type-2 diabetes (T2D). The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) is an essential, upstream component of the inflammatory cascade....
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717797/ https://ncbi.nlm.nih.gov/pubmed/19478200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.199166 |
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