MIF-deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance and associated atherosclerotic disease

Chronic inflammation in white adipose tissue (WAT) is positively associated with obesity, insulin resistance (IR) and the development of type-2 diabetes (T2D). The pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) is an essential, upstream component of the inflammatory cascade....

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Auteurs principaux: Verschuren, Lars, Kooistra, Teake, Bernhagen, Jürgen, Voshol, Peter J., Ouwens, D. Margriet, van Erk, Marjan, de Vries-van der Weij, Jitske, Leng, Lin, van Bockel, J. Hajo, van Dijk, Ko Willems, Fingerle-Rowson, Günter, Bucala, Rick, Kleemann, Robert
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717797/
https://ncbi.nlm.nih.gov/pubmed/19478200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.199166
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