Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease

BACKGROUND: Clinical studies have demonstrated that 50% of individuals with chronic renal disease (CRD) die of cardiovascular causes, including advanced calcific arterial and valvular disease; however, the mechanisms of accelerated calcification in CRD remain obscure, and no therapies can prevent di...

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Autori principali: Aikawa, Elena, Aikawa, Masanori, Libby, Peter, Figueiredo, Jose-Luiz, Rusanescu, Gabriel, Iwamoto, Yoshiko, Fukuda, Daiju, Kohler, Rainer H., Shi, Guo-Ping, Jaffer, Farouc A., Weissleder, Ralph
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717745/
https://ncbi.nlm.nih.gov/pubmed/19307473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.827972
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