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Development of a microtiter plate based assay for lipid linked glycosyl transferase products using the mycobacterial cell wall rhamnosyl transferase, WbbL

In Mycobacterium tuberculosis a rhamnosyl transferase (WbbL) catalyzes the transfer of an α-L-Rhap residue from dTDP-Rha to decaprenyldiphosphoryl-α-D-N-acetyl glucosamine (GlcNAc-P-P-DP) to form α-L-Rhap-(1→3)-α-D-GlcNAc-P-P-DP, which is then further elongated with Galf and Araf units and finally m...

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Detalhes bibliográficos
Main Authors: Grzegorzewicz, Anna E., Ma, Yufang, Jones, Victoria, Crick, Dean, Liav, Avraham, McNeil, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717732/
https://ncbi.nlm.nih.gov/pubmed/19047740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.2008/023366-0
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