Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase

UDP-N-acetyl-D-glucosamine (UDP-GlcNAc) is an essential precursor of peptidoglycan and the rhamnose-GlcNAc linker region of mycobacterial cell wall. In Mycobacterium tuberculosis H37Rv genome, Rv1018c shows strong homology to the GlmU protein involved in the formation of UDP-GlcNAc from other bacter...

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Main Authors: Zhang, Wenli, Jones, Victoria C., Scherman, Michael S., Mahapatra, Sebabrata, Crick, Dean, Bhamidi, Suresh, Xin, Yi, McNeil, Michael R., Ma, Yufang
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602953/
https://ncbi.nlm.nih.gov/pubmed/18573680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.05.003
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