The Activation Of ATM Depends On Chromatin Interactions Occurring Prior To DNA-Damage Induction

Efficient and correct responses to double stranded breaks (DSB) in chromosomal DNA are critical for maintaining genomic stability and preventing chromosomal alterations leading to cancer1. The generation of DSB is associated with structural changes in chromatin and the activation of the protein kina...

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Bibliografiske detaljer
Main Authors: Kim, Yong-Chul, Gerlitz, Gabi, Furusawa, Takashi, Catez, Frédéric, Nussenzweig, Andre, Oh, Kyu-Seon, Kraemer, Kenneth H., Shiloh, Yosef, Bustin, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717731/
https://ncbi.nlm.nih.gov/pubmed/19079244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1817
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