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Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro

The impact of ageing in innate immunity is poorly understood. Studies in the mouse model have described altered innate immune functions in aged macrophages, although these were not generally linked to altered expression of receptors or regulatory molecules. Moreover, the influence of ageing in the e...

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Autors principals: Liang, Shuang, Domon, Hisanori, Hosur, Kavita B., Wang, Min, Hajishengallis, George
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717634/
https://ncbi.nlm.nih.gov/pubmed/19559723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.06.006
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