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Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro

The impact of ageing in innate immunity is poorly understood. Studies in the mouse model have described altered innate immune functions in aged macrophages, although these were not generally linked to altered expression of receptors or regulatory molecules. Moreover, the influence of ageing in the e...

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Bibliographic Details
Main Authors: Liang, Shuang, Domon, Hisanori, Hosur, Kavita B., Wang, Min, Hajishengallis, George
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717634/
https://ncbi.nlm.nih.gov/pubmed/19559723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.06.006
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