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Interaction of two arginine residues in lactate oxidase with the enzyme flavin: Conversion of FMN to 8-formyl-FMN

Two arginine residues, Arg-181 and Arg-268, are conserved throughout the known family of FMN-containing enzymes that catalyze the oxidation of α-hydroxyacids. In the lactate oxidase from Aerococcus viridans, these residues have been changed to lysine in two single mutations and in a double mutant fo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yorita, Kazuko, Matsuoka, Takeshi, Misaki, Hideo, Massey, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11078532/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.250472297
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