Metabolic Activity Determines Efficacy of Macroautophagic Clearance of Pathological Oligomeric α-Synuclein

Macroautophagy is an essential degradative pathway that can be induced to clear aggregated proteins, such as those found in Parkinson’s disease and dementia with Lewy bodies, a form of Parkinsonism. This study found that both LC3-II and beclin were significantly increased in brains from humans with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yu, Wai Haung, Dorado, Beatriz, Figueroa, Helen Yvette, Wang, Lili, Planel, Emmanuel, Cookson, Mark R., Clark, Lorraine N., Duff, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716969/
https://ncbi.nlm.nih.gov/pubmed/19628769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080928
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
A carregar...

Registos relacionados