Inhibition of Receptor Activator of NF-κB Ligand by Denosumab Attenuates Vascular Calcium Deposition in Mice

Osteoporosis and vascular calcification frequently coincide. A potential mediator of bone metabolism and vascular homeostasis is the triad cytokine system, which consists of receptor activator of nuclear factor-κB (RANK) ligand (RANKL), its receptor RANK, and the decoy receptor osteoprotegerin. Unop...

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Detalhes bibliográficos
Main Authors: Helas, Susann, Goettsch, Claudia, Schoppet, Michael, Zeitz, Ute, Hempel, Ute, Morawietz, Henning, Kostenuik, Paul J., Erben, Reinhold G., Hofbauer, Lorenz C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716948/
https://ncbi.nlm.nih.gov/pubmed/19590040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080957
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