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Inhibition of Lactoperoxidase by Its Own Catalytic Product: Crystal Structure of the Hypothiocyanate-Inhibited Bovine Lactoperoxidase at 2.3-Å Resolution

To the best of our knowledge, this is the first report on the structure of product-inhibited mammalian peroxidase. Lactoperoxidase is a heme containing an enzyme that catalyzes the inactivation of a wide range of microorganisms. In the presence of hydrogen peroxide, it preferentially converts thiocy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Singh, A.K., Singh, Nagendra, Sharma, Sujata, Shin, Kouichirou, Takase, Mitsunori, Kaur, Punit, Srinivasan, A., Singh, T.P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Biophysical Society 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716474/
https://ncbi.nlm.nih.gov/pubmed/19167310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.09.019
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