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Finding and Characterizing Tunnels in Macromolecules with Application to Ion Channels and Pores

We describe a new algorithm, CHUNNEL, to automatically find, characterize, and display tunnels or pores in proteins. The correctness and accuracy of the algorithm is verified on a constructed set of proteins and used to analyze large sets of real proteins. The verification set contains proteins with...

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Detalhes bibliográficos
Main Authors: Coleman, Ryan G., Sharp, Kim A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716472/
https://ncbi.nlm.nih.gov/pubmed/18849407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.135970
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