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Orally available Mn porphyrins with superoxide dismutase and catalase activities

Superoxide dismutase/catalase mimetics, such as salen Mn complexes and certain metalloporphyrins, catalytically neutralize reactive oxygen and nitrogen species, which have been implicated in the pathogenesis of many serious diseases. Both classes of mimetic are protective in animal models of oxidati...

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Bibliographic Details
Main Authors: Rosenthal, Rosalind A., Huffman, Karl D., Fisette, Leslie W., Damphousse, Christy A., Callaway, Wyeth B., Malfroy, Bernard, Doctrow, Susan R.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716445/
https://ncbi.nlm.nih.gov/pubmed/19504132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-009-0550-4
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