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Foxd3 Controls Melanophore Specification in the Zebrafish Neural Crest by Regulation of Mitf
We describe a mechanistic model whereby Foxd3, a forkhead transcription factor, prevents neural crest-derived precursors from acquiring a melanophore fate. Foxd3 regulates this fate choice by repressing the mitfa promoter in a subset of neural crest cells. mitfa is only expressed in a Foxd3-negative...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716409/ https://ncbi.nlm.nih.gov/pubmed/19527705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.06.010 |
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