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Foxd3 Controls Melanophore Specification in the Zebrafish Neural Crest by Regulation of Mitf

We describe a mechanistic model whereby Foxd3, a forkhead transcription factor, prevents neural crest-derived precursors from acquiring a melanophore fate. Foxd3 regulates this fate choice by repressing the mitfa promoter in a subset of neural crest cells. mitfa is only expressed in a Foxd3-negative...

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Detalhes bibliográficos
Main Authors: Curran, Kevin, Raible, David W., Lister, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716409/
https://ncbi.nlm.nih.gov/pubmed/19527705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.06.010
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