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FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism

The first neural crest cells to emigrate from the neural tube are specified as neurons and glial cells and are subsequently followed by melanocytes of the skin. We wished to understand how this fate switch is controlled. The transcriptional repressor FOXD3 is expressed exclusively in the neural/glia...

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Detalhes bibliográficos
Main Authors: Thomas, Aaron J., Erickson, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680109/
https://ncbi.nlm.nih.gov/pubmed/19403660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.031989
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