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Characterization of Rationally Attenuated Francisella tularensis Vaccine Strains That Harbor Deletions in the guaA and guaB Genes

Francisella tularensis, the etiologic agent of tularemia, can cause severe and fatal infection after inhalation of as few as 10-100 CFU. F. tularensis is a potential bioterrorism agent and, therefore, a priority for countermeasure development. Vaccination with the live vaccine strain (LVS), develope...

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Detalhes bibliográficos
Main Authors: Santiago, Araceli E., Cole, Leah E., Franco, Augusto, Vogel, Stefanie N., Levine, Myron M., Barry, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716139/
https://ncbi.nlm.nih.gov/pubmed/19368784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.02.073
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