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Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive α(1) Na(+)-K(+)-ATPase

Endogenous Na(+) pump inhibitors are thought to play important (patho)physiological roles and occur in two different chemical forms in the mammalian circulation: cardenolides, such as ouabain, and bufadienolides, such as marinobufagenin (MBG). Although all α Na(+)-K(+)-ATPase isoforms (α(1-4)) are s...

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Detalhes bibliográficos
Main Authors: Wansapura, Arshani N., Lasko, Valerie, Xie, Zijian, Fedorova, Olga V., Bagrov, Alexei Y., Lingrel, Jerry B, Lorenz, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716102/
https://ncbi.nlm.nih.gov/pubmed/19376809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00285.2009
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