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Lipid peroxidation upregulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer’s disease
Increased lipid peroxidation is shown to be an early event of AD. However, it is not clear whether and how increased lipid peroxidation might lead to amyloidogenesis, a hallmark of AD. Gpx4 is an essential antioxidant defense enzyme that protects an organism against lipid peroxidation. Gpx4(+/-) mic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716044/ https://ncbi.nlm.nih.gov/pubmed/18680556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05603.x |
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