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The Fanconi Anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly
Fanconi Anemia (FA) is a chromosome instability syndrome characterized by congenital abnormalities, cellular hypersensitivity to DNA crosslinking agents, and heightened cancer risk. Eight of the thirteen identified FA genes encode subunits of a nuclear FA core complex that monoubiquitinates FANCD2 a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715953/ https://ncbi.nlm.nih.gov/pubmed/18448394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.001 |
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