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The Pro-Fibrotic Factor IGFBP-5 Induces Lung Fibroblast and Mononuclear Cell Migration

We have previously shown that insulin-like growth factor–binding protein-5 (IGFBP-5) is overexpressed in fibrotic lung tissues and that it induces production of extracellular matrix components such as collagen and fibronectin both in vitro and in vivo. We recently observed mononuclear cell infiltrat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yasuoka, Hidekata, Yamaguchi, Yukie, Feghali-Bostwick, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715907/
https://ncbi.nlm.nih.gov/pubmed/19131643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0211OC
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