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Lack of Bax Prevents Influenza A Virus-Induced Apoptosis and Causes Diminished Viral Replication

The ectopic overexpression of Bcl-2 restricts both influenza A virus-induced apoptosis and influenza A virus replication in MDCK cells, thus suggesting a role for Bcl-2 family members during infection. Here we report that influenza A virus cannot establish an apoptotic response without functional Ba...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McLean, Jeffrey E., Datan, Emmanuel, Matassov, Demetrius, Zakeri, Zahra F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715773/
https://ncbi.nlm.nih.gov/pubmed/19494020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02672-08
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