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Combinations of the First and Next Generations of Human Immunodeficiency Virus (HIV) Fusion Inhibitors Exhibit a Highly Potent Synergistic Effect against Enfuvirtide- Sensitive and -Resistant HIV Type 1 Strains

T20 (generic name, enfuvirtide; brand name, Fuzeon) is a first-generation human immunodeficiency virus (HIV) fusion inhibitor approved for salvage therapy of HIV-infected patients refractory to current antiretroviral drugs. However, its clinical use is limited because of rapid emergence of T20-resis...

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Detalhes bibliográficos
Main Authors: Pan, Chungen, Cai, Lifeng, Lu, Hong, Qi, Zhi, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715752/
https://ncbi.nlm.nih.gov/pubmed/19493996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00168-09
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