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Generation of Antigenic Variants via Gene Conversion: Evidence for Recombination Fitness Selection at the Locus Level in Anaplasma marginale

Multiple bacterial and protozoal pathogens utilize gene conversion to generate antigenically variant surface proteins to evade immune clearance and establish persistent infection. Both the donor alleles that encode the variants following recombination into an expression site and the donor loci thems...

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Detalles Bibliográficos
Autores principales: Futse, James E., Brayton, Kelly A., Nydam, Seth D., Palmer, Guy H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715667/
https://ncbi.nlm.nih.gov/pubmed/19487473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00348-09
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