Selection for Simple Major Surface Protein 2 Variants during Anaplasma marginale Transmission to Immunologically Naïve Animals

Anaplasma marginale, a rickettsial pathogen, evades clearance in the animal host by antigenic variation. Under immune selection, A. marginale expresses complex major surface protein 2 mosaics, derived from multiple donor sequences. However, these mosaics have a selective advantage only in the presen...

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Bibliografiska uppgifter
Huvudupphovsmän: Palmer, Guy H., Futse, James E., Leverich, Christina K., Knowles, Donald P., Rurangirwa, Fred R., Brayton, Kelly A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Bacterial Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828556/
https://ncbi.nlm.nih.gov/pubmed/17178787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01801-06
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