Anidulafungin Is Fungicidal and Exerts a Variety of Postantifungal Effects against Candida albicans, C. glabrata, C. parapsilosis, and C. krusei isolates

Anidulafungin targets the cell walls of Candida species by inhibiting β-1,3-glucan synthase, thereby killing isolates and exerting prolonged postantifungal effects (PAFEs). We performed time-kill and PAFE experiments on Candida albicans (n = 4), C. glabrata (n = 3), C. parapsilosis (n = 3), and C. k...

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Detalhes bibliográficos
Main Authors: Nguyen, Katherine T., Ta, Philip, Hoang, Bich Thu, Cheng, Shaoji, Hao, Binghua, Nguyen, M. Hong, Clancy, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715634/
https://ncbi.nlm.nih.gov/pubmed/19364856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01480-08
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