Measurement of Voriconazole Activity against Candida albicans, C. glabrata, and C. parapsilosis Isolates Using Time-Kill Methods Validated by High-Performance Liquid Chromatography

We developed a high-performance liquid chromatography (HPLC) assay to validate time-kill and postantifungal-effect (PAFE) experiments for voriconazole against Candida albicans, Candida glabrata, and Candida parapsilosis isolates. Voriconazole exerted prolonged fungistatic activity but no PAFE at con...

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Detalhes bibliográficos
Main Authors: Li, Yanjun, Nguyen, M. Hong, Derendorf, Hartmut, Cheng, Shaoji, Clancy, Cornelius J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932531/
https://ncbi.nlm.nih.gov/pubmed/17517840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00308-07
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