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Antibodies to the Polymeric Immunoglobulin Receptor with Different Binding and Trafficking Patterns

The polymeric immunoglobulin receptor (pIgR) has been proposed as a therapeutic target, but its potential depends on the efficiency of uptake and trafficking of the receptor ligand. Mouse monoclonal antibodies (Mabs) directed against pIgR, selected for strong binding to secretory component (SC) and...

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Bibliografiske detaljer
Main Authors: Gupta, Sanhita, Heacock, Michael, Perez, Aura, Davis, Pamela B.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715344/
https://ncbi.nlm.nih.gov/pubmed/15994431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0132OC
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