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Dimerization of the Polymeric Immunoglobulin Receptor Controls Its Transcytotic Trafficking

Binding of dimeric immunoglobulin (Ig)A to the polymeric Ig receptor (pIgR) stimulates transcytosis of pIgR across epithelial cells. Through the generation of a series of pIgR chimeric constructs, we have tested the ability of ligand to promote receptor dimerization and the subsequent role of recept...

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Autori principali: Singer, Karen L., Mostov, Keith E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC25316/
https://ncbi.nlm.nih.gov/pubmed/9529387
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