Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

Neural stem cell (NSC) transplantation represents an unexplored approach for treating neurodegenerative disorders associated with cognitive decline such as Alzheimer disease (AD). Here, we used aged triple transgenic mice (3xTg-AD) that express pathogenic forms of amyloid precursor protein, presenil...

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Bibliographische Detailangaben
Hauptverfasser: Blurton-Jones, Mathew, Kitazawa, Masashi, Martinez-Coria, Hilda, Castello, Nicholas A., Müller, Franz-Josef, Loring, Jeanne F., Yamasaki, Tritia R., Poon, Wayne W., Green, Kim N., LaFerla, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715325/
https://ncbi.nlm.nih.gov/pubmed/19633196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901402106
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