Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

Neural stem cell (NSC) transplantation represents an unexplored approach for treating neurodegenerative disorders associated with cognitive decline such as Alzheimer disease (AD). Here, we used aged triple transgenic mice (3xTg-AD) that express pathogenic forms of amyloid precursor protein, presenil...

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Bibliographic Details
Main Authors: Blurton-Jones, Mathew, Kitazawa, Masashi, Martinez-Coria, Hilda, Castello, Nicholas A., Müller, Franz-Josef, Loring, Jeanne F., Yamasaki, Tritia R., Poon, Wayne W., Green, Kim N., LaFerla, Frank M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715325/
https://ncbi.nlm.nih.gov/pubmed/19633196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901402106
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