Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

Neural stem cell (NSC) transplantation represents an unexplored approach for treating neurodegenerative disorders associated with cognitive decline such as Alzheimer disease (AD). Here, we used aged triple transgenic mice (3xTg-AD) that express pathogenic forms of amyloid precursor protein, presenil...

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Detalhes bibliográficos
Main Authors: Blurton-Jones, Mathew, Kitazawa, Masashi, Martinez-Coria, Hilda, Castello, Nicholas A., Müller, Franz-Josef, Loring, Jeanne F., Yamasaki, Tritia R., Poon, Wayne W., Green, Kim N., LaFerla, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715325/
https://ncbi.nlm.nih.gov/pubmed/19633196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901402106
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