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Active Uptake of Dendritic Cell-Derived Exovesicles by Epithelial Cells Induces the Release of Inflammatory Mediators through a TNF-α-Mediated Pathway

Dendritic cells (DCs) can release hundreds of membrane vesicles, called exovesicles, which are able to activate resting DCs and distribute antigen. Here, we examined the role of mature DC-derived exovesicles in innate and adaptive immunity, in particular their capacity to activate epithelial cells....

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Main Authors: Obregon, Carolina, Rothen-Rutishauser, Barbara, Gerber, Peter, Gehr, Peter, Nicod, Laurent P.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715287/
https://ncbi.nlm.nih.gov/pubmed/19628765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080716
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