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Active Uptake of Dendritic Cell-Derived Exovesicles by Epithelial Cells Induces the Release of Inflammatory Mediators through a TNF-α-Mediated Pathway

Dendritic cells (DCs) can release hundreds of membrane vesicles, called exovesicles, which are able to activate resting DCs and distribute antigen. Here, we examined the role of mature DC-derived exovesicles in innate and adaptive immunity, in particular their capacity to activate epithelial cells....

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Autors principals: Obregon, Carolina, Rothen-Rutishauser, Barbara, Gerber, Peter, Gehr, Peter, Nicod, Laurent P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715287/
https://ncbi.nlm.nih.gov/pubmed/19628765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080716
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