Active Uptake of Dendritic Cell-Derived Exovesicles by Epithelial Cells Induces the Release of Inflammatory Mediators through a TNF-α-Mediated Pathway

Dendritic cells (DCs) can release hundreds of membrane vesicles, called exovesicles, which are able to activate resting DCs and distribute antigen. Here, we examined the role of mature DC-derived exovesicles in innate and adaptive immunity, in particular their capacity to activate epithelial cells....

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Bibliografiska uppgifter
Huvudupphovsmän: Obregon, Carolina, Rothen-Rutishauser, Barbara, Gerber, Peter, Gehr, Peter, Nicod, Laurent P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2009
Ämnen:
Regular Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715287/
https://ncbi.nlm.nih.gov/pubmed/19628765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080716
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