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ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion

Arabidopsis ROS1 belongs to a family of plant 5-methycytosine DNA glycosylases that initiate DNA demethylation through base excision. ROS1 displays the remarkable capacity to excise 5-meC, and to a lesser extent T, while retaining the ability to discriminate effectively against C and U. We found tha...

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Bibliografiske detaljer
Main Authors: Ponferrada-Marín, María Isabel, Roldán-Arjona, Teresa, Ariza, Rafael R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715244/
https://ncbi.nlm.nih.gov/pubmed/19443451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp390
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