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Signaling cascades as drug targets in model and pathogenic fungi

Microbes evolved to produce natural products that inhibit growth of competing soil microorganisms. In many cases, these compounds act on fungi, which are eukaryotes closely related to metazoans, including humans. The calcineurin inhibitors CsA and FK506, the Tor inhibitor rapamycin, and the Hsp90 in...

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Detalhes bibliográficos
Main Authors: Bastidas, Robert J, Reedy, Jennifer L, Morales-Johansson, Helena, Heitman, Joseph, Cardenas, Maria E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715221/
https://ncbi.nlm.nih.gov/pubmed/18666033
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