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Dynamic Effect of Bortezomib on NF-κB Activity and Gene Expression in Tumor Cells
NF-κB influences the initiation, progression, and maintenance of diverse cancer types. Despite current therapeutic efforts to block hyperactive NF-κB in cancer cells, the in vivo effects of a drug upon this complex pathway are unclear. We monitored NF-κB activity and a fast-expressing reporter level...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715175/ https://ncbi.nlm.nih.gov/pubmed/18684839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.049114 |
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