Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

Netherton syndrome (NS) is a severe genetic skin disease with constant atopic manifestations that is caused by mutations in the serine protease inhibitor Kazal-type 5 (SPINK5) gene, which encodes the protease inhibitor lymphoepithelial Kazal-type–related inhibitor (LEKTI). Lack of LEKTI causes strat...

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Main Authors: Briot, Anaïs, Deraison, Céline, Lacroix, Matthieu, Bonnart, Chrystelle, Robin, Aurélie, Besson, Céline, Dubus, Pierre, Hovnanian, Alain
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715042/
https://ncbi.nlm.nih.gov/pubmed/19414552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082242
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