Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria

Urticarial rash observed in cryopyrin-associated periodic syndrome (CAPS) caused by nucleotide-binding oligomerization domain–leucine-rich repeats containing pyrin domain 3 (NLRP3) mutations is effectively suppressed by anti–interleukin (IL)-1 treatment, suggesting a pathophysiological role of IL-1β...

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Hlavní autoři: Nakamura, Yuumi, Kambe, Naotomo, Saito, Megumu, Nishikomori, Ryuta, Kim, Yun-Gi, Murakami, Makoto, Núñez, Gabriel, Matsue, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715029/
https://ncbi.nlm.nih.gov/pubmed/19364881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082179
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