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A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers
The CHEK2 1100delC protein-truncating mutation has a carrier frequency of ~0.7% in Northern and Western European populations and confers an ~2-fold increased risk of breast cancer. It has also been suggested to increase risks of colorectal and prostate cancer, but its involvement with these or other...
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主要な著者: | , , , , , , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2006
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714971/ https://ncbi.nlm.nih.gov/pubmed/17164383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-06-0687 |
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