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A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation Carriers
The CHEK2 1100delC protein-truncating mutation has a carrier frequency of ~0.7% in Northern and Western European populations and confers an ~2-fold increased risk of breast cancer. It has also been suggested to increase risks of colorectal and prostate cancer, but its involvement with these or other...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2006
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714971/ https://ncbi.nlm.nih.gov/pubmed/17164383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-06-0687 |
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