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HSP90α and HSP90β Isoforms Selectively Modulate MHC Class II Antigen Presentation in B cells

Two isoforms of HSP90, α and β, are abundantly expressed in the cytoplasm of cells, yet only HSP90α serves as a chaperone to potentiate epitope presentation in the context of MHC class I molecules. By contrast, the role of HSP90 isoforms in MHC class II presentation of exogenous and endogenous Ags r...

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Détails bibliographiques
Auteurs principaux: Houlihan, Josetta L., Metzler, Jennifer J., Blum, Janice S.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714911/
https://ncbi.nlm.nih.gov/pubmed/19494268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804296
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