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Significant effect of APOE Epsilon 4 genotype on the risk of Alzheimer’s disease and mortality In persons with Down syndrome
OBJECTIVE: Virtually all adults with Down syndrome (DS) have neuropathological manifestations of Alzheimer’s disease (AD) but not all develop the condition. The effect of allelic variants of Apolipoprotein (APOE) gene in the development and progression of AD and mortality in people with DS is examin...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714805/ https://ncbi.nlm.nih.gov/pubmed/18464295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gps.2039 |
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