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Tissue prostanoids as biomarkers for chemoprevention of colorectal neoplasia: correlation between prostanoid synthesis and clinical response in familial adenomatous polyposis

Recent studies indicate that sulindac, a nonsteroidal anti-inflammatory drug (NSAID), lowers mucosal prostanoid levels and regresses colorectal adenomas in patients with familial adenomatous polyposis (FAP). To determine whether they are biomarkers for sulindac-mediated chemoprevention of colorectal...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Vincent W., Geiman, Deborah E., Hubbard, Walter C., Spannhake, Ernst W., Hylind, Linda M., Hamilton, Stanley R., Giardiello, Francis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714803/
https://ncbi.nlm.nih.gov/pubmed/10680778
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