Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures

Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone receptor family, which is defined as transcriptional factors that are activated by the binding of ligands to their ligand-binding domains (LBDs). Although the three PPAR subtypes display different tissue distribution p...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Oyama, Takuji, Toyota, Kenji, Waku, Tsuyoshi, Hirakawa, Yuko, Nagasawa, Naoko, Kasuga, Jun-ichi, Hashimoto, Yuichi, Miyachi, Hiroyuki, Morikawa, Kosuke
פורמט: Artigo
שפה:Inglês
יצא לאור: International Union of Crystallography 2009
נושאים:
Research Papers
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714719/
https://ncbi.nlm.nih.gov/pubmed/19622862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909015935
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