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Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning
The abundance of retinoic acid (RA) is determined by the balance between its synthesis by retinaldehyde dehydrogenase (RALDH) and its degradation by CYP26. In particular, the dynamic expression of three CYP26 genes controls the regional level of RA within the body. Pregastrulation mouse embryos expr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714714/ https://ncbi.nlm.nih.gov/pubmed/19605690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1776209 |
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