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Experimental diabetes in rats causes hippocampal dendritic and synaptic reorganization and increased glucocorticoid reactivity to stress

We report that 9 d of uncontrolled experimental diabetes induced by streptozotocin (STZ) in rats is an endogenous chronic stressor that produces retraction and simplification of apical dendrites of hippocampal CA3 pyramidal neurons, an effect also observed in nondiabetic rats after 21 d of repeated...

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Détails bibliographiques
Auteurs principaux: Magariños, Ana María, McEwen, Bruce S.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC27147/
https://ncbi.nlm.nih.gov/pubmed/11005876
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